As I experienced, the Densha De Go series are working on every PC without any problem. At the installation you can see a lot of "?" "@" and other letters instead of Japanese characters, but it can't be a problem for a PC user, just push Enter, Enter, Enter to reach Next, Next, Next!

For your info: there are some pieces from the DDG series that are priced for JPY 1480 and JPY 1980.